Formulation design for delivery. For a molecule already selected.
For pharmaceutical and nutraceutical ingredient, formulation and contract manufacturing businesses: we model the formulation problem for an existing molecule and design a test of the limiting step.
What we doThe landscape
The tools exist
Poor aqueous solubility has been worked on for decades, and well. Amorphous solid dispersions, lipid-based and self-emulsifying systems, nanocrystals, cyclodextrins, salt and co-crystal forms are established and in industrial use. We are not offering a replacement for them.
The established routes are answers. Which step still holds a particular molecule back is a different question.
Our role
One molecule. One question.
We do not replace your formulation team; we start where its last attempt ended.
We do not work on biologics and we do not work on minerals.
- THE SITUATION
- A molecule already characterised in your own data, now stalled at the formulation stage.
- PRIOR WORK
- Routes already tried are not lost work: each one narrows where the limiting step can be.
- THE MODEL
- The model uses your data to explain which step limits the molecule.
- EXCIPIENTS
- We design with established, well-documented excipients rather than novel materials.
- THE DATA WE USE
- We work on data: what your team already has, and what the test produces.
- THE FINDING
- Can the target performance be reached within the stated assumptions? If not, we say so.
The working sequence
From question to test data
The question
Model the limiting step against your existing formulation performance.
The experiment
Write the assumptions, test design and question before the test runs.
The build
The designed formulation is made for your molecule by a contract manufacturer before the test.
The reading
The laboratory tests the formulation; we read the data it returns.
The written report
What comes back
- THE QUESTION
The target the work addresses.
- THE ASSUMPTIONS
The conditions the answer depends on.
- THE LIMITING STEP
The explanation to put to the test.
- THE EXPERIMENT
The comparison set out before testing.
- THE READING
The test data considered against the explanation.
- THE ANSWER
A written conclusion, including what remains open.
In brief
What to expect
What is needed for a first conversation?
An outline of where formulation work has stalled is enough to begin.
Does Pheraxia replace the team or receive material?
Your team keeps its role; Pheraxia receives information, never the physical material.
Where is it made and tested?
Your material goes to the manufacturer that makes the formulation for your molecule, then to the laboratory for testing.
What if the answer is no?
The report explains why the target is unsupported under the stated assumptions.
Starting conditions
Before we start
This work starts with one stalled molecule, not a portfolio.
You have a molecule your own data already supports, and no product from it yet.
THE MOLECULEYou have tried the standard formulation approaches. The question has not been closed.
THE ROUTESYou want to know which step still fails — and whether a path exists.
THE LIMITYou have the prior experimental data from that work, or can arrange access to it.
THE DATAYou have, or can arrange, the manufacturing step and the laboratory test.
THE CAPACITY
Describe the formulation problem in a first conversation.
THE NEXT STEPGet in touch
Tell us about the problem, not the molecule.
A first conversation needs no structures and no formulations — only the problem you are trying to solve.
Please share nothing confidential in a first conversation.
info@pheraxia.com